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Deoxyribonuclease I Activity, Cell-Free DNA, and Risk of Liver Cancer in a Prospective Cohort
BACKGROUND: Circulating cell-free DNA (cfDNA) is a proposed latent biomarker for several cancers, including liver cancer. Deoxyribonucleases (DNases) facilitate the timely and efficient degradation of cfDNA, leading us to hypothesize that DNase I and/or II might be a more sensitive early biomarker t...
Autores principales: | Golonka, Rachel M, Yeoh, Beng San, Petrick, Jessica L, Weinstein, Stephanie J, Albanes, Demetrius, Gewirtz, Andrew T, McGlynn, Katherine A, Vijay-Kumar, Matam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383694/ https://www.ncbi.nlm.nih.gov/pubmed/30815627 http://dx.doi.org/10.1093/jncics/pky083 |
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