Enhanced Activation of Rac1/Cdc42 and MITF Leads to Augmented Osteoclastogenesis in Autosomal Dominant Osteopetrosis Type II

The autosomal dominant osteopetrosis type II (ADOII) caused by the mutation of chloride channel 7 (ClC‐7) gene is the most common form of adult‐onset osteopetrosis. Despite dysfunctional bone resorption, an augmented osteoclast differentiation was reported recently in ADOII patients. DNA sequencing...

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Detalles Bibliográficos
Autores principales: Jung, Youn‐Kwan, Kwon, Ki‐Tae, Jang, Ji‐Ae, Han, Min‐Su, Kim, Gun‐Woo, Han, Seungwoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Novel Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383696/
https://www.ncbi.nlm.nih.gov/pubmed/30828687
http://dx.doi.org/10.1002/jbm4.10070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383696/
https://www.ncbi.nlm.nih.gov/pubmed/30828687
http://dx.doi.org/10.1002/jbm4.10070

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