Sexually dimorphic tumor suppression by small mitochondrial Arf

Internal translational initiation of the mRNA encoding the Arf tumor suppressor yields an N-terminally truncated small Arf protein (smArf) that lacks amino acid residues required for Mdm2 binding and p53 activation. Here, we report that female, but not male, mice engineered to produce only smArf in...

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Detalles Bibliográficos
Autores principales: van Oosterwijk, Jolieke G., Tillman, Heather, Sherr, Charles J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Priority Research Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383814/
https://www.ncbi.nlm.nih.gov/pubmed/30815226
http://dx.doi.org/10.18632/oncotarget.26651

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383814/
https://www.ncbi.nlm.nih.gov/pubmed/30815226
http://dx.doi.org/10.18632/oncotarget.26651

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