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Sexually dimorphic tumor suppression by small mitochondrial Arf
Internal translational initiation of the mRNA encoding the Arf tumor suppressor yields an N-terminally truncated small Arf protein (smArf) that lacks amino acid residues required for Mdm2 binding and p53 activation. Here, we report that female, but not male, mice engineered to produce only smArf in...
Autores principales: | van Oosterwijk, Jolieke G., Tillman, Heather, Sherr, Charles J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383814/ https://www.ncbi.nlm.nih.gov/pubmed/30815226 http://dx.doi.org/10.18632/oncotarget.26651 |
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