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Testing for goodness rather than lack of fit of an X–chromosomal SNP to the Hardy-Weinberg model

The problem of checking the genotype distribution obtained for some diallelic marker for compatibility with the Hardy-Weinberg equilibrium (HWE) condition arises also for loci on the X chromosome. The possible genotypes depend on the sex of the individual in this case: for females, the genotype dist...

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Detalles Bibliográficos
Autores principales: Wellek, Stefan, Ziegler, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383894/
https://www.ncbi.nlm.nih.gov/pubmed/30789927
http://dx.doi.org/10.1371/journal.pone.0212344