Molecular recognition and maturation of SOD1 by its evolutionarily destabilised cognate chaperone hCCS

Superoxide dismutase-1 (SOD1) maturation comprises a string of posttranslational modifications which transform the nascent peptide into a stable and active enzyme. The successive folding, metal ion binding, and disulphide acquisition steps in this pathway can be catalysed through a direct interactio...

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Detalles Bibliográficos
Autores principales: Sala, Fernanda A., Wright, Gareth S. A., Antonyuk, Svetlana V., Garratt, Richard C., Hasnain, S. Samar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383938/
https://www.ncbi.nlm.nih.gov/pubmed/30735496
http://dx.doi.org/10.1371/journal.pbio.3000141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383938/
https://www.ncbi.nlm.nih.gov/pubmed/30735496
http://dx.doi.org/10.1371/journal.pbio.3000141

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