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Fast and flexible linear mixed models for genome-wide genetics
Linear mixed effect models are powerful tools used to account for population structure in genome-wide association studies (GWASs) and estimate the genetic architecture of complex traits. However, fully-specified models are computationally demanding and common simplifications often lead to reduced po...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383949/ https://www.ncbi.nlm.nih.gov/pubmed/30735486 http://dx.doi.org/10.1371/journal.pgen.1007978 |