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Optimization Workflow for the Analysis of Cross-Linked Peptides Using a Quadrupole Time-of-Flight Mass Spectrometer

[Image: see text] Cross-linking mass spectrometry is an emerging structural biology technique. Almost exclusively, the analyzer of choice for such an experiment has been the Orbitrap. We present an optimized protocol for the use of a Synapt G2-Si for the analysis of cross-linked peptides. We first t...

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Detalles Bibliográficos
Autores principales: James, Juliette M. B., Cryar, Adam, Thalassinos, Konstantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383985/
https://www.ncbi.nlm.nih.gov/pubmed/30620560
http://dx.doi.org/10.1021/acs.analchem.8b02319