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Ephrin-B3 controls excitatory synapse density through cell-cell competition for EphBs

Cortical networks are characterized by sparse connectivity, with synapses found at only a subset of axo-dendritic contacts. Yet within these networks, neurons can exhibit high connection probabilities, suggesting that cell-intrinsic factors, not proximity, determine connectivity. Here, we identify e...

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Detalles Bibliográficos
Autores principales: Henderson, Nathan T, Le Marchand, Sylvain J, Hruska, Martin, Hippenmeyer, Simon, Luo, Liqun, Dalva, Matthew B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384025/
https://www.ncbi.nlm.nih.gov/pubmed/30789343
http://dx.doi.org/10.7554/eLife.41563