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The Interaction of Bluetongue Virus VP6 and Genomic RNA Is Essential for Genome Packaging

The genomes of the Reoviridae, including the animal pathogen bluetongue virus (BTV), are multisegmented double-stranded RNA (dsRNA). During replication, single-stranded (ss) positive-sense RNA segments are packaged into the assembling virus capsid, triggering genomic dsRNA synthesis. However, exactl...

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Detalles Bibliográficos
Autores principales: Sung, Po-Yu, Vaughan, Robert, Rahman, Shah Kamranur, Yi, Guanghui, Kerviel, Adeline, Kao, C. Cheng, Roy, Polly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384066/
https://www.ncbi.nlm.nih.gov/pubmed/30541863
http://dx.doi.org/10.1128/JVI.02023-18