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Beneficial effects of andrographolide in a rat model of autoimmune myocarditis and its effects on PI3K/Akt pathway

The study is to investigate effects of andrographolide on experimental autoimmune myocarditis (EAM). Lewis rats were immunized on day 0 with porcine cardiac myosin to establish EAM. The EAM rats were treated with either andrographolide (25, 50, 100 mg/kg/day) or vehicle for 21 days. An antigen-speci...

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Detalles Bibliográficos
Autores principales: Zhang, Qi, Hu, Li-qun, Li, Hong-qi, Wu, Jun, Bian, Na-na, Yan, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384199/
https://www.ncbi.nlm.nih.gov/pubmed/30820154
http://dx.doi.org/10.4196/kjpp.2019.23.2.103