Fast Amide Bond Cleavage Assisted by a Secondary Amino and a Carboxyl Group—A Model for yet Unknown Peptidases?

Unconstrained amides that undergo fast hydrolysis under mild conditions are valuable sources of information about how amide bonds may be activated in enzymatic transformations. We report a compound possessing an unconstrained amide bond surrounded by an amino and a carboxyl group, each mounted in cl...

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Detalles Bibliográficos
Autores principales: V. Komarov, Igor, Yu. Ishchenko, Aleksandr, Hovtvianitsa, Aleksandr, Stepanenko, Viacheslav, Kharchenko, Serhii, D. Bond, Andrew, J. Kirby, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384577/
https://www.ncbi.nlm.nih.gov/pubmed/30764512
http://dx.doi.org/10.3390/molecules24030572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384577/
https://www.ncbi.nlm.nih.gov/pubmed/30764512
http://dx.doi.org/10.3390/molecules24030572

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