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Synergistic Effects of The Enhancements to Mitochondrial ROS, p53 Activation and Apoptosis Generated by Aspartame and Potassium Sorbate in HepG2 Cells

The safety of food additives has been widely concerned. Using single additives in the provisions of scope is safe, but the combination of additives, may induce additive, synergy, antagonism and other joint effects. This study investigated the cytotoxicity of aspartame (AT) together with potassium so...

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Detalles Bibliográficos
Autores principales: Qu, Daofeng, Jiang, Mengxue, Huang, Dongping, Zhang, Hui, Feng, Lifang, Chen, Yuewen, Zhu, Xuan, Wang, Suhua, Han, Jianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384600/
https://www.ncbi.nlm.nih.gov/pubmed/30696035
http://dx.doi.org/10.3390/molecules24030457