Developing Novel G-Quadruplex Ligands: From Interaction with Nucleic Acids to Interfering with Nucleic Acid–Protein Interaction

G-quadruplex is a special secondary structure of nucleic acids in guanine-rich sequences of genome. G-quadruplexes have been proved to be involved in the regulation of replication, DNA damage repair, and transcription and translation of oncogenes or other cancer-related genes. Therefore, targeting G...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Zhi-Yin, Wang, Xiao-Na, Cheng, Sui-Qi, Su, Xiao-Xuan, Ou, Tian-Miao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384609/
https://www.ncbi.nlm.nih.gov/pubmed/30678288
http://dx.doi.org/10.3390/molecules24030396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384609/
https://www.ncbi.nlm.nih.gov/pubmed/30678288
http://dx.doi.org/10.3390/molecules24030396

Ejemplares similares