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Evaluation of MMP Inhibitors Isolated from Ligustrum japonicum Fructus

The current study investigated the ability of two secoiridoids, GL-3 (1) and oleonuezhenide (2), isolated from the fruits of Ligustrum japonicum to inhibit MMP-2 and -9 activity in phorbol 12-myristate 13-acetate (PMA)-induced HT-1080 human fibrosarcoma cells. Both compounds 1 and 2 were able to exe...

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Detalles Bibliográficos
Autores principales: Kim, Hojun, Karadeniz, Fatih, Kong, Chang-Suk, Seo, Youngwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384611/
https://www.ncbi.nlm.nih.gov/pubmed/30744075
http://dx.doi.org/10.3390/molecules24030604