Investigating the Effect of Mono- and Dimeric 360A G-Quadruplex Ligands on Telomere Stability by Single Telomere Length Analysis (STELA)

Telomeres are nucleoprotein structures that cap and protect the natural ends of chromosomes. Telomeric DNA G-rich strands can form G-quadruplex (or G4) structures. Ligands that bind to and stabilize G4 structures can lead to telomere dysfunctions by displacing shelterin proteins and/or by interferin...

Descripción completa

Detalles Bibliográficos
Autores principales: Hwang, In Pyo, Mailliet, Patrick, Hossard, Virginie, Riou, Jean-Francois, Bugaut, Anthony, Roger, Lauréline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384687/
https://www.ncbi.nlm.nih.gov/pubmed/30736276
http://dx.doi.org/10.3390/molecules24030577

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384687/
https://www.ncbi.nlm.nih.gov/pubmed/30736276
http://dx.doi.org/10.3390/molecules24030577

Ejemplares similares