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Astilbin Inhibits the Activity of Sortase A from Streptococcus mutans

Streptococcus mutans (S. mutans) is the primary etiological agent of dental caries. The S. mutans enzyme sortase A (SrtA) is responsible for anchoring bacterial cell wall surface proteins involved in host cell attachment and biofilm formation. Thus, SrtA is an attractive target for inhibiting dental...

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Detalles Bibliográficos
Autores principales: Wang, Junxian, Shi, Yan, Jing, Shisong, Dong, Haisi, Wang, Dacheng, Wang, Tiedong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384703/
https://www.ncbi.nlm.nih.gov/pubmed/30696091
http://dx.doi.org/10.3390/molecules24030465