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The Cardiotoxicity Induced by Arsenic Trioxide is Alleviated by Salvianolic Acid A via Maintaining Calcium Homeostasis and Inhibiting Endoplasmic Reticulum Stress

Arsenic trioxide (ATO) has been verified as a breakthrough with respect to the management of acute promyelocytic leukemia (APL) in recent decades but associated with some serious adverse phenomena, particularly cardiac functional abnormalities. Salvianolic acid A (Sal A) is a major effective compone...

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Detalles Bibliográficos
Autores principales: Wang, Ruiying, Zhang, Jingyi, Wang, Shan, Wang, Min, Ye, Tianyuan, Du, Yuyang, Xie, Xueheng, Ye, Jingxue, Sun, Guibo, Sun, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384753/
https://www.ncbi.nlm.nih.gov/pubmed/30717322
http://dx.doi.org/10.3390/molecules24030543