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The Cardiotoxicity Induced by Arsenic Trioxide is Alleviated by Salvianolic Acid A via Maintaining Calcium Homeostasis and Inhibiting Endoplasmic Reticulum Stress
Arsenic trioxide (ATO) has been verified as a breakthrough with respect to the management of acute promyelocytic leukemia (APL) in recent decades but associated with some serious adverse phenomena, particularly cardiac functional abnormalities. Salvianolic acid A (Sal A) is a major effective compone...
Autores principales: | Wang, Ruiying, Zhang, Jingyi, Wang, Shan, Wang, Min, Ye, Tianyuan, Du, Yuyang, Xie, Xueheng, Ye, Jingxue, Sun, Guibo, Sun, Xiaobo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384753/ https://www.ncbi.nlm.nih.gov/pubmed/30717322 http://dx.doi.org/10.3390/molecules24030543 |
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