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Design, Synthesis, Docking Studies and Monoamine Oxidase Inhibition of a Small Library of 1-acetyl- and 1-thiocarbamoyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazoles

New N-acetyl/N-thiocarbamoylpyrazoline derivatives were designed and synthesized in high yields to assess their inhibitory activity and selectivity against human monoamine oxidase A and B. The most important chiral compounds were separated into their single enantiomers and tested. The impact of the...

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Detalles Bibliográficos
Autores principales:	Guglielmi, Paolo, Carradori, Simone, Poli, Giulio, Secci, Daniela, Cirilli, Roberto, Rotondi, Giulia, Chimenti, Paola, Petzer, Anél, Petzer, Jacobus P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384781/ https://www.ncbi.nlm.nih.gov/pubmed/30700029 http://dx.doi.org/10.3390/molecules24030484

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