Novel Approach for the Search for Chemical Scaffolds with Activity at Both Acetylcholinesterase and the α7 Nicotinic Acetylcholine Receptor: A Perspective on Scaffolds with Dual Activity for the Treatment of Neurodegenerative Disorders

Neurodegenerative disorders, including Alzheimer’s disease, belong to the group of the most difficult and challenging conditions with very limited treatment options. Attempts to find new drugs in most cases fail at the clinical stage. New tactics to develop better drug candidates to manage these dis...

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Detalles Bibliográficos
Autores principales: Kowal, Natalia M., Indurthi, Dinesh C., Ahring, Philip K., Chebib, Mary, Olafsdottir, Elin S., Balle, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384821/
https://www.ncbi.nlm.nih.gov/pubmed/30691196
http://dx.doi.org/10.3390/molecules24030446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384821/
https://www.ncbi.nlm.nih.gov/pubmed/30691196
http://dx.doi.org/10.3390/molecules24030446

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