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Novel Approach for the Search for Chemical Scaffolds with Activity at Both Acetylcholinesterase and the α7 Nicotinic Acetylcholine Receptor: A Perspective on Scaffolds with Dual Activity for the Treatment of Neurodegenerative Disorders
Neurodegenerative disorders, including Alzheimer’s disease, belong to the group of the most difficult and challenging conditions with very limited treatment options. Attempts to find new drugs in most cases fail at the clinical stage. New tactics to develop better drug candidates to manage these dis...
Autores principales: | Kowal, Natalia M., Indurthi, Dinesh C., Ahring, Philip K., Chebib, Mary, Olafsdottir, Elin S., Balle, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384821/ https://www.ncbi.nlm.nih.gov/pubmed/30691196 http://dx.doi.org/10.3390/molecules24030446 |
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