The Bispidinone Derivative 3,7-Bis-[2-(S)-amino-3-(1H-indol-3-yl)-propionyl]-1,5-diphenyl-3,7-diazabicyclo[3.3.1]nonan-9-one Dihydrochloride Induces an Apoptosis-Mediated Cytotoxic Effect on Pancreatic Cancer Cells In Vitro

Pancreatic cancer (PC) is a complex, heterogeneous disease with a dismal prognosis. Current therapies have failed to improve survival outcomes, urging the need for discovery of novel targeted treatments. Bispidinone derivatives have yet to be investigated as cytotoxic agents against PC cells. The cy...

Descripción completa

Detalles Bibliográficos
Autores principales: Predebon, Melanie J., Bond, Danielle R., Brzozowski, Joshua, Jankowski, Helen, Deane, Fiona, Tarleton, Mark, Shaw, Aron A., McCluskey, Adam, Bowyer, Michael C., Weidenhofer, Judith, Scarlett, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384835/
https://www.ncbi.nlm.nih.gov/pubmed/30709047
http://dx.doi.org/10.3390/molecules24030524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384835/
https://www.ncbi.nlm.nih.gov/pubmed/30709047
http://dx.doi.org/10.3390/molecules24030524

Ejemplares similares