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An automated microliter-scale high-throughput screening system (MSHTS) for real-time monitoring of protein aggregation using quantum-dot nanoprobes

Protein aggregation is the principal component of numerous protein misfolding pathologies termed proteinopathies, such as Alzheimer’s disease, Parkinson’s disease, prion disease, and AA amyloidosis with unmet treatment needs. Protein aggregation inhibitors have great potential for the prevention and...

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Detalles Bibliográficos
Autores principales: Sasaki, Rina, Tainaka, Reina, Ando, Yuichi, Hashi, Yurika, Deepak, Hadya V., Suga, Yoshiko, Murai, Yuta, Anetai, Masaki, Monde, Kenji, Ohta, Kiminori, Ito, Ikuko, Kikuchi, Haruhisa, Oshima, Yoshiteru, Endo, Yasuyuki, Nakao, Hitomi, Sakono, Masafumi, Uwai, Koji, Tokuraku, Kiyotaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384891/
https://www.ncbi.nlm.nih.gov/pubmed/30796247
http://dx.doi.org/10.1038/s41598-019-38958-0