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An automated microliter-scale high-throughput screening system (MSHTS) for real-time monitoring of protein aggregation using quantum-dot nanoprobes
Protein aggregation is the principal component of numerous protein misfolding pathologies termed proteinopathies, such as Alzheimer’s disease, Parkinson’s disease, prion disease, and AA amyloidosis with unmet treatment needs. Protein aggregation inhibitors have great potential for the prevention and...
Autores principales: | Sasaki, Rina, Tainaka, Reina, Ando, Yuichi, Hashi, Yurika, Deepak, Hadya V., Suga, Yoshiko, Murai, Yuta, Anetai, Masaki, Monde, Kenji, Ohta, Kiminori, Ito, Ikuko, Kikuchi, Haruhisa, Oshima, Yoshiteru, Endo, Yasuyuki, Nakao, Hitomi, Sakono, Masafumi, Uwai, Koji, Tokuraku, Kiyotaka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384891/ https://www.ncbi.nlm.nih.gov/pubmed/30796247 http://dx.doi.org/10.1038/s41598-019-38958-0 |
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