Heterosubtypic cross-protection correlates with cross-reactive interferon-gamma-secreting lymphocytes in the ferret model of influenza

An effective universal vaccine for influenza will likely need to induce virus-specific T-cells, which are the major mediator of heterosubtypic cross-protection between different subtypes of influenza A virus. In this study we characterise the cell-mediated immune response in ferrets during heterosub...

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Detalles Bibliográficos
Autores principales: Gooch, Karen E., Marriott, Anthony C., Ryan, Kathryn A., Yeates, Paul, Slack, Gillian S., Brown, Phillip J., Fothergill, Ross, Whittaker, Catherine J., Carroll, Miles W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384896/
https://www.ncbi.nlm.nih.gov/pubmed/30796267
http://dx.doi.org/10.1038/s41598-019-38885-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384896/
https://www.ncbi.nlm.nih.gov/pubmed/30796267
http://dx.doi.org/10.1038/s41598-019-38885-0

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