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Heterosubtypic cross-protection correlates with cross-reactive interferon-gamma-secreting lymphocytes in the ferret model of influenza
An effective universal vaccine for influenza will likely need to induce virus-specific T-cells, which are the major mediator of heterosubtypic cross-protection between different subtypes of influenza A virus. In this study we characterise the cell-mediated immune response in ferrets during heterosub...
Autores principales: | Gooch, Karen E., Marriott, Anthony C., Ryan, Kathryn A., Yeates, Paul, Slack, Gillian S., Brown, Phillip J., Fothergill, Ross, Whittaker, Catherine J., Carroll, Miles W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384896/ https://www.ncbi.nlm.nih.gov/pubmed/30796267 http://dx.doi.org/10.1038/s41598-019-38885-0 |
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