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Increased 5-HT2C receptor editing predisposes to PTSD-like behaviors and alters BDNF and cytokines signaling

Post-traumatic stress disorder (PTSD) is a trauma- and stress-related disorder with dysregulated fear responses and neurobiological impairments, notably at neurotrophic and inflammation levels. Understanding the mechanisms underlying this disease is crucial to develop PTSD models that meet behaviora...

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Detalles Bibliográficos
Autores principales: Règue, Mathilde, Poilbout, Corinne, Martin, Vincent, Franc, Bernard, Lanfumey, Laurence, Mongeau, Raymond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384909/
https://www.ncbi.nlm.nih.gov/pubmed/30792491
http://dx.doi.org/10.1038/s41398-019-0431-8