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Exploring the suitability of RanBP2-type Zinc Fingers for RNA-binding protein design

Transcriptomes consist of several classes of RNA that have wide-ranging but often poorly described functions and the deregulation of which leads to numerous diseases. Engineering of functionalized RNA-binding proteins (RBPs) could therefore have many applications. Our previous studies suggested that...

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Detalles Bibliográficos
Autores principales: De Franco, Simona, Vandenameele, Julie, Brans, Alain, Verlaine, Olivier, Bendak, Katerina, Damblon, Christian, Matagne, André, Segal, David J., Galleni, Moreno, Mackay, Joel P., Vandevenne, Marylène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384913/
https://www.ncbi.nlm.nih.gov/pubmed/30792407
http://dx.doi.org/10.1038/s41598-019-38655-y