Design, Synthesis and Biological Evaluation of Nitrate Derivatives of Sauropunol A and B as Potent Vasodilatory Agents

A group of nitrate derivatives of naturally occurring sauropunol A and B were designed and synthesized. Nitric oxide (NO) releasing capacity and vasodilatory capacity studies were performed to explore the structure-activity relationship of resulted nitrates. Biological evaluation of these compounds...

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Detalles Bibliográficos
Autores principales: Lu, Lu, Rao, Xuemin, Cong, Rigang, Zhang, Chenxi, Wang, Zhimei, Xu, Jinyi, Tanabe, Genzoh, Muraoka, Osamu, Wu, Xiaoming, Xie, Weijia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384914/
https://www.ncbi.nlm.nih.gov/pubmed/30736379
http://dx.doi.org/10.3390/molecules24030583

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384914/
https://www.ncbi.nlm.nih.gov/pubmed/30736379
http://dx.doi.org/10.3390/molecules24030583

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