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Design, Synthesis and Biological Evaluation of Nitrate Derivatives of Sauropunol A and B as Potent Vasodilatory Agents
A group of nitrate derivatives of naturally occurring sauropunol A and B were designed and synthesized. Nitric oxide (NO) releasing capacity and vasodilatory capacity studies were performed to explore the structure-activity relationship of resulted nitrates. Biological evaluation of these compounds...
Autores principales: | Lu, Lu, Rao, Xuemin, Cong, Rigang, Zhang, Chenxi, Wang, Zhimei, Xu, Jinyi, Tanabe, Genzoh, Muraoka, Osamu, Wu, Xiaoming, Xie, Weijia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384914/ https://www.ncbi.nlm.nih.gov/pubmed/30736379 http://dx.doi.org/10.3390/molecules24030583 |
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