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Microwave-Assisted Stereoselective Heterocyclization to Novel Ring d-fused Arylpyrazolines in the Estrone Series

Microwave-assisted syntheses of novel ring d-condensed 2-pyrazolines in the estrone series were efficiently carried out from steroidal α,β-enones and hydrazine derivatives. The ring-closure reaction of 16-benzylidene estrone 3-methyl ether with hydrazine in acetic acid resulted in a 2:1 diastereomer...

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Detalles Bibliográficos
Autores principales: Mótyán, Gergő, Molnár, Barnabás, Wölfling, János, Frank, Éva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384934/
https://www.ncbi.nlm.nih.gov/pubmed/30720767
http://dx.doi.org/10.3390/molecules24030569