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BRAF V600E and SRC mutations as molecular markers for predicting prognosis and conversion surgery in Stage IV colorectal cancer

Comprehensive genomic sequencing (CGS) enables us to detect numerous genetic alterations in a single assay. We aimed to identify molecular markers for predicting prognosis and conversion surgery in Stage IV colorectal cancer (CRC) using CGS. One-hundred eleven patients with Stage IV CRC who underwen...

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Detalles Bibliográficos
Autores principales: Shimada, Yoshifumi, Muneoka, Yusuke, Nagahashi, Masayuki, Ichikawa, Hiroshi, Tajima, Yosuke, Hirose, Yuki, Ando, Takuya, Nakano, Masato, Sakata, Jun, Kameyama, Hitoshi, Takii, Yasumasa, Ling, Yiwei, Okuda, Shujiro, Takabe, Kazuaki, Wakai, Toshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384937/
https://www.ncbi.nlm.nih.gov/pubmed/30792536
http://dx.doi.org/10.1038/s41598-019-39328-6