Cargando…

BRAF V600E and SRC mutations as molecular markers for predicting prognosis and conversion surgery in Stage IV colorectal cancer

Comprehensive genomic sequencing (CGS) enables us to detect numerous genetic alterations in a single assay. We aimed to identify molecular markers for predicting prognosis and conversion surgery in Stage IV colorectal cancer (CRC) using CGS. One-hundred eleven patients with Stage IV CRC who underwen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shimada, Yoshifumi, Muneoka, Yusuke, Nagahashi, Masayuki, Ichikawa, Hiroshi, Tajima, Yosuke, Hirose, Yuki, Ando, Takuya, Nakano, Masato, Sakata, Jun, Kameyama, Hitoshi, Takii, Yasumasa, Ling, Yiwei, Okuda, Shujiro, Takabe, Kazuaki, Wakai, Toshifumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384937/ https://www.ncbi.nlm.nih.gov/pubmed/30792536 http://dx.doi.org/10.1038/s41598-019-39328-6

Ejemplares similares

RNF43 mutation is associated with aggressive tumor biology along with BRAF V600E mutation in right-sided colorectal cancer
por: Matsumoto, Akio, et al.
Publicado: (2020)

Next generation sequencing‐based gene panel tests for the management of solid tumors
por: Nagahashi, Masayuki, et al.
Publicado: (2018)

SMAD4 alteration associates with invasive‐front pathological markers and poor prognosis in colorectal cancer
por: Oyanagi, Hidehito, et al.
Publicado: (2019)

Genomic characterization of colitis-associated colorectal cancer
por: Kameyama, Hitoshi, et al.
Publicado: (2018)

Genetic profiling for diffuse type and genomically stable subtypes in gastric cancer
por: Ling, Yiwei, et al.
Publicado: (2020)

Unveiling microbiome profiles in human inner body fluids and tumor tissues with pancreatic or biliary tract cancer
por: Okuda, Shujiro, et al.
Publicado: (2022)

Comprehensive genomic sequencing detects important genetic differences between right-sided and left-sided colorectal cancer
por: Shimada, Yoshifumi, et al.
Publicado: (2017)

Profiling of host genetic alterations and intra-tumor microbiomes in colorectal cancer
por: Okuda, Shujiro, et al.
Publicado: (2021)

Axillary cutaneous metastasis of colon cancer with microsatellite instability-high and BRAF V600E mutation treated with curative-intent surgery: a case report
por: Yamai, Daisuke, et al.
Publicado: (2023)

Pathogenic Germline BRCA1/2 Mutations and Familial Predisposition to Gastric Cancer
por: Ichikawa, Hiroshi, et al.
Publicado: (2018)

Generation of sphingosine-1-phosphate is enhanced in biliary tract cancer patients and is associated with lymphatic metastasis
por: Hirose, Yuki, et al.
Publicado: (2018)

Plasma Sphingosine-1-Phosphate Levels Are Associated with Progression of Estrogen Receptor-Positive Breast Cancer
por: Ikarashi, Mayuko, et al.
Publicado: (2021)

Gene panel testing detects important genetic alterations in ulcerative colitis-associated colorectal neoplasia
por: Shimada, Yoshifumi, et al.
Publicado: (2022)

Advanced Stage Is a Risk for Severe Neutropenia in Breast Cancer Patients Undergoing Neoadjuvant Adriamycin/Cyclophosphamide/Docetaxel Chemotherapy
por: Moro, Kazuki, et al.
Publicado: (2022)

Hyperbilirubinemia predicts the infectious complications after esophagectomy for esophageal cancer
por: Muneoka, Yusuke, et al.
Publicado: (2019)

Impact of Concurrent Genomic Alterations Detected by Comprehensive Genomic Sequencing on Clinical Outcomes in East-Asian Patients with EGFR-Mutated Lung Adenocarcinoma
por: Sato, Seijiro, et al.
Publicado: (2018)

Prophylactic lateral pelvic lymph node dissection in stage IV low rectal cancer
por: Tamura, Hiroshi, et al.
Publicado: (2017)

Actionable gene-based classification toward precision medicine in gastric cancer
por: Ichikawa, Hiroshi, et al.
Publicado: (2017)

Clinical Impact of Sphingosine-1-Phosphate in Breast Cancer
por: Tsuchida, Junko, et al.
Publicado: (2017)

Long-term survival in pseudo-Meigs’ syndrome caused by ovarian metastases from colon cancer
por: Tajima, Yosuke, et al.
Publicado: (2016)

Genetic analysis in the clinical management of biliary tract cancer
por: Wakai, Toshifumi, et al.
Publicado: (2020)

Primary lung squamous cell carcinoma and its association with gastric metastasis: A case report and literature review
por: Nemoto, Mariko, et al.
Publicado: (2020)

Do Preys Prey on Their Predators? Confusion over Predatory “Hage-taka” Journals
por: Takabe, Kazuaki, et al.
Publicado: (2019)

Oral Administration of Glucosylceramide Suppresses Tumor Growth by Affecting the Ceramide/Sphingosine-1-Phosphate Balance in Breast Cancer Tissue
por: Moro, Kazuki, et al.
Publicado: (2023)

Clinical Significance of Extramural Tumor Deposits in the Lateral Pelvic Lymph Node Area in Low Rectal Cancer: A Retrospective Study at Two Institutions
por: Yagi, Ryoma, et al.
Publicado: (2016)

Genomic landscape of colorectal cancer in Japan: clinical implications of comprehensive genomic sequencing for precision medicine
por: Nagahashi, Masayuki, et al.
Publicado: (2016)

Hypermutation and microsatellite instability in gastrointestinal cancers
por: Yuza, Kizuki, et al.
Publicado: (2017)

The role of sphingosine‐1‐phosphate in inflammation and cancer progression
por: Nagahashi, Masayuki, et al.
Publicado: (2018)

At what age should screening mammography be recommended for Asian women?
por: Tsuchida, Junko, et al.
Publicado: (2015)

Accuracy of the endoscopic evaluation of esophageal involvement in esophagogastric junction cancer
por: Sakai, Takeshi, et al.
Publicado: (2021)

Small Bowel Obstruction After Ileal Pouch-Anal Anastomosis With a Loop Ileostomy in Patients With Ulcerative Colitis
por: Kameyama, Hitoshi, et al.
Publicado: (2018)

Sphingosine-1-Phosphate Transporters as Targets for Cancer Therapy
por: Nagahashi, Masayuki, et al.
Publicado: (2014)

A giant pelvic solitary fibrous tumor with Doege–Potter syndrome successfully treated with transcatheter arterial embolization followed by surgical resection: a case report
por: Yuza, Kizuki, et al.
Publicado: (2020)

Sphingosine-1-phosphate in the lymphatic fluid determined by novel methods
por: Nagahashi, Masayuki, et al.
Publicado: (2016)

Dramatic response of BRAF V600E-mutant epithelioid glioblastoma to combination therapy with BRAF and MEK inhibitor: establishment and xenograft of a cell line to predict clinical efficacy
por: Kanemaru, Yu, et al.
Publicado: (2019)

Left colic artery aneurysm rupture after stent placement for abdominal aortic aneurysm associated with neurofibromatosis type 1
por: Moro, Kazuki, et al.
Publicado: (2019)

Intravenous Carnitine Administration in Addition to Parenteral Nutrition With Lipid Emulsion May Decrease the Inflammatory Reaction in Postoperative Surgical Patients
por: Koyama, Yu, et al.
Publicado: (2017)

Association between poorly differentiated clusters and efficacy of 5-fluorouracil-based adjuvant chemotherapy in stage III colorectal cancer
por: Tajima, Yosuke, et al.
Publicado: (2017)

Conservative treatment of idiopathic spontaneous pneumoperitoneum in a bedridden patient: a case report
por: Tanaka, Ryo, et al.
Publicado: (2015)

Hand-assisted laparoscopic Hassab’s procedure for esophagogastric varices with portal hypertension
por: Kobayashi, Takashi, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_t13ffs1hb5hngi61dpq5dgij02