The β-N-Acetylhexosaminidase in the Synthesis of Bioactive Glycans: Protein and Reaction Engineering

N-Acetylhexosamine oligosaccharides terminated with GalNAc act as selective ligands of galectin-3, a biomedically important human lectin. Their synthesis can be accomplished by β-N-acetylhexosaminidases (EC 3.2.1.52). Advantageously, these enzymes tolerate the presence of functional groups in the su...

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Detalles Bibliográficos
Autores principales: Bojarová, Pavla, Kulik, Natalia, Hovorková, Michaela, Slámová, Kristýna, Pelantová, Helena, Křen, Vladimír
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384963/
https://www.ncbi.nlm.nih.gov/pubmed/30743988
http://dx.doi.org/10.3390/molecules24030599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384963/
https://www.ncbi.nlm.nih.gov/pubmed/30743988
http://dx.doi.org/10.3390/molecules24030599

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