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The β-N-Acetylhexosaminidase in the Synthesis of Bioactive Glycans: Protein and Reaction Engineering
N-Acetylhexosamine oligosaccharides terminated with GalNAc act as selective ligands of galectin-3, a biomedically important human lectin. Their synthesis can be accomplished by β-N-acetylhexosaminidases (EC 3.2.1.52). Advantageously, these enzymes tolerate the presence of functional groups in the su...
Autores principales: | Bojarová, Pavla, Kulik, Natalia, Hovorková, Michaela, Slámová, Kristýna, Pelantová, Helena, Křen, Vladimír |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384963/ https://www.ncbi.nlm.nih.gov/pubmed/30743988 http://dx.doi.org/10.3390/molecules24030599 |
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