One-Pot Synthesis of Triazolobenzodiazepines Through Decarboxylative [3 + 2] Cycloaddition of Nonstabilized Azomethine Ylides and Cu-Free Click Reactions

A one-pot synthesis of triazolobenzodiazepine-containing polycyclic compounds is introduced. The reaction process involves a decarboxylative three-component [3 + 2] cycloaddition of nonstabilized azomethine ylides, N-propargylation, and intramolecular click reactions.

Detalles Bibliográficos
Autores principales: Ma, Xiaoming, Zhang, Xiaofeng, Qiu, Weiqi, Zhang, Wensheng, Wan, Bruce, Evans, Jason, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384988/
https://www.ncbi.nlm.nih.gov/pubmed/30743991
http://dx.doi.org/10.3390/molecules24030601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384988/
https://www.ncbi.nlm.nih.gov/pubmed/30743991
http://dx.doi.org/10.3390/molecules24030601

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