5-Arylideneimidazolones with Amine at Position 3 as Potential Antibiotic Adjuvants against Multidrug Resistant Bacteria

Searching for new chemosensitizers of bacterial multidrug resistance (MDR), chemical modifications of (Z)-5-(4-chlorobenzylidene)-2-(4-methylpiperazin-1-yl)-3H-imidazol-4(5H)-one (6) were performed. New compounds (7–17), with fused aromatic rings at position 5, were designed and synthesized. Crystal...

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Detalles Bibliográficos
Autores principales: Kaczor, Aneta, Witek, Karolina, Podlewska, Sabina, Czekajewska, Joanna, Lubelska, Annamaria, Żesławska, Ewa, Nitek, Wojciech, Latacz, Gniewomir, Alibert, Sandrine, Pagès, Jean-Marie, Karczewska, Elżbieta, Kieć-Kononowicz, Katarzyna, Handzlik, Jadwiga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384991/
https://www.ncbi.nlm.nih.gov/pubmed/30691112
http://dx.doi.org/10.3390/molecules24030438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384991/
https://www.ncbi.nlm.nih.gov/pubmed/30691112
http://dx.doi.org/10.3390/molecules24030438

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