Cargando…
5-Arylideneimidazolones with Amine at Position 3 as Potential Antibiotic Adjuvants against Multidrug Resistant Bacteria
Searching for new chemosensitizers of bacterial multidrug resistance (MDR), chemical modifications of (Z)-5-(4-chlorobenzylidene)-2-(4-methylpiperazin-1-yl)-3H-imidazol-4(5H)-one (6) were performed. New compounds (7–17), with fused aromatic rings at position 5, were designed and synthesized. Crystal...
Autores principales: | Kaczor, Aneta, Witek, Karolina, Podlewska, Sabina, Czekajewska, Joanna, Lubelska, Annamaria, Żesławska, Ewa, Nitek, Wojciech, Latacz, Gniewomir, Alibert, Sandrine, Pagès, Jean-Marie, Karczewska, Elżbieta, Kieć-Kononowicz, Katarzyna, Handzlik, Jadwiga |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384991/ https://www.ncbi.nlm.nih.gov/pubmed/30691112 http://dx.doi.org/10.3390/molecules24030438 |
Ejemplares similares
-
Molecular Insights into an Antibiotic Enhancer Action of New Morpholine-Containing 5-Arylideneimidazolones in the Fight against MDR Bacteria
por: Kaczor, Aneta, et al.
Publicado: (2021) -
Phenylpiperazine 5,5-Dimethylhydantoin Derivatives as First Synthetic Inhibitors of Msr(A) Efflux Pump in Staphylococcus epidermidis
por: Witek, Karolina, et al.
Publicado: (2020) -
Search for ABCB1 Modulators Among 2-Amine-5-Arylideneimidazolones as a New Perspective to Overcome Cancer Multidrug Resistance
por: Kaczor, Aneta, et al.
Publicado: (2020) -
Chalcogen-Varied Imidazolone Derivatives as Antibiotic Resistance Breakers in Staphylococcus aureus Strains
por: Witek, Karolina, et al.
Publicado: (2023) -
Studies on Anticonvulsant Effects of Novel Histamine H3R Antagonists in Electrically and Chemically Induced Seizures in Rats
por: Alachkar, Alaa, et al.
Publicado: (2018)