A Straightforward Synthesis of Functionalized cis-Perhydroisoquinolin-1-ones

Base-catalyzed annulation reactions of 5,6-dihydro-2(1H)-pyridones with Nazarov-type reagents are reported. The effect of the solvent polarity and the concentration of the reagents is studied. The process involves two successive Michael additions and stereoselectively provides functionalized cis-per...

Descripción completa

Detalles Bibliográficos
Autores principales: Arioli, Federica, Pérez, Maria, Are, Celeste, Molins, Elies, Bosch, Joan, Amat, Mercedes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385050/
https://www.ncbi.nlm.nih.gov/pubmed/30717460
http://dx.doi.org/10.3390/molecules24030557

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385050/
https://www.ncbi.nlm.nih.gov/pubmed/30717460
http://dx.doi.org/10.3390/molecules24030557

Ejemplares similares