mRNA Polyplexes with Post-Conjugated GALA Peptides Efficiently Target, Transfect, and Activate Antigen Presenting Cells

[Image: see text] Vaccines based on mRNA have emerged as potent systems to elicit CD8(+) T cell responses against various cancers and viral infectious diseases. The efficient intracellular delivery of mRNA molecules encoding antigens into the cytosol of antigen-presenting cells (APCs) is still chall...

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Detalles Bibliográficos
Autores principales: Lou, Bo, De Koker, Stefaan, Lau, Chun Yin Jerry, Hennink, Wim E., Mastrobattista, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385079/
https://www.ncbi.nlm.nih.gov/pubmed/30188694
http://dx.doi.org/10.1021/acs.bioconjchem.8b00524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385079/
https://www.ncbi.nlm.nih.gov/pubmed/30188694
http://dx.doi.org/10.1021/acs.bioconjchem.8b00524

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