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mRNA Polyplexes with Post-Conjugated GALA Peptides Efficiently Target, Transfect, and Activate Antigen Presenting Cells
[Image: see text] Vaccines based on mRNA have emerged as potent systems to elicit CD8(+) T cell responses against various cancers and viral infectious diseases. The efficient intracellular delivery of mRNA molecules encoding antigens into the cytosol of antigen-presenting cells (APCs) is still chall...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385079/ https://www.ncbi.nlm.nih.gov/pubmed/30188694 http://dx.doi.org/10.1021/acs.bioconjchem.8b00524 |