Design and Synthesis of Arylamidine Derivatives as Serotonin/Norepinephrine Dual Reuptake Inhibitors

To improve the in vivo antidepressant activity of previously reported serotonin (5-HT) and norepinephrine (NE) dual reuptake inhibitors, three series of arylamidine derivatives were designed and synthesized. The in vitro 5-HT and NE reuptake inhibitory activities of these compounds were evaluated, a...

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Detalles Bibliográficos
Autores principales: Wen, Hui, Qin, Wen, Yang, Guangzhong, Guo, Yanshen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385122/
https://www.ncbi.nlm.nih.gov/pubmed/30704101
http://dx.doi.org/10.3390/molecules24030497

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385122/
https://www.ncbi.nlm.nih.gov/pubmed/30704101
http://dx.doi.org/10.3390/molecules24030497

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