Design, Synthesis, Anticancer Evaluation and Molecular Modeling of Novel Estrogen Derivatives

A series of estrone derivatives 3–8 was designed and synthesized using estrone arylmethylenes 2a,b as starting materials and their structures were confirmed by different spectral data and elemental analyses. All the newly synthesized compounds exhibited potent in vitro and in vivo cytotoxic activiti...

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Detalles Bibliográficos
Autores principales: Amr, Abd El-Galil E., Elsayed, Elsayed A., Al-Omar, Mohamed A., Badr Eldin, Hanan O., Nossier, Eman S., Abdallah, Mohamed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385123/
https://www.ncbi.nlm.nih.gov/pubmed/30678347
http://dx.doi.org/10.3390/molecules24030416

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385123/
https://www.ncbi.nlm.nih.gov/pubmed/30678347
http://dx.doi.org/10.3390/molecules24030416

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