pKa Determination of a Histidine Residue in a Short Peptide Using Raman Spectroscopy

Determining the pKa of key functional groups is critical to understanding the pH-dependent behavior of biological proteins and peptide-based biomaterials. Traditionally, (1)H NMR spectroscopy has been used to determine the pKa of amino acids; however, for larger molecules and aggregating systems, th...

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Detalles Bibliográficos
Autores principales: Pogostin, Brett H., Malmendal, Anders, Londergan, Casey H., Åkerfeldt, Karin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385126/
https://www.ncbi.nlm.nih.gov/pubmed/30678032
http://dx.doi.org/10.3390/molecules24030405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385126/
https://www.ncbi.nlm.nih.gov/pubmed/30678032
http://dx.doi.org/10.3390/molecules24030405

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