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pKa Determination of a Histidine Residue in a Short Peptide Using Raman Spectroscopy
Determining the pKa of key functional groups is critical to understanding the pH-dependent behavior of biological proteins and peptide-based biomaterials. Traditionally, (1)H NMR spectroscopy has been used to determine the pKa of amino acids; however, for larger molecules and aggregating systems, th...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385126/ https://www.ncbi.nlm.nih.gov/pubmed/30678032 http://dx.doi.org/10.3390/molecules24030405 |