Anti-inflammatory effect of afatinib (an EGFR-TKI) on OGD-induced neuroinflammation

Activated epidermal growth factor receptor (EGFR) has been proposed in the pathophysiology of neurodegenerative diseases. In the present study, the anti-inflammatory effect of afatinib, an EGFR-tyrosine kinase inhibitor (EGFR-TKIs) was investigated using CTX-TNA2 cells and primary cultured astrocyte...

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Detalles Bibliográficos
Autores principales: Chen, Yen-Ju, Hsu, Chia-Chi, Shiao, Young-Ji, Wang, Hsiang-Tsui, Lo, Yu-Li, Lin, A. M. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385176/
https://www.ncbi.nlm.nih.gov/pubmed/30792526
http://dx.doi.org/10.1038/s41598-019-38676-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385176/
https://www.ncbi.nlm.nih.gov/pubmed/30792526
http://dx.doi.org/10.1038/s41598-019-38676-7

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