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Changes in microbiome diversity following beta-lactam antibiotic treatment are associated with therapeutic versus subtherapeutic antibiotic exposure in cystic fibrosis

In persons with cystic fibrosis (CF), decreased airway microbial diversity is associated with lower lung function. Conflicting data exist on the impact of short-term antibiotics for treatment of acute pulmonary exacerbations. However, whether differences in antibiotic exposure impacts airway microbi...

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Detalles Bibliográficos
Autores principales: Hahn, Andrea, Fanous, Hani, Jensen, Caroline, Chaney, Hollis, Sami, Iman, Perez, Geovanny F., Koumbourlis, Anastassios C., Louie, Stan, Bost, James E., van den Anker, John N., Freishtat, Robert J., Zemanick, Edith T., Crandall, Keith A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385179/
https://www.ncbi.nlm.nih.gov/pubmed/30796252
http://dx.doi.org/10.1038/s41598-019-38984-y