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Somatic mutations of PREX2 gene in patients with hepatocellular carcinoma

Characterized with a high recurrence rate and low detection rate, prevention is the best approach to reduce mortality in hepatocellular carcinoma (HCC). The overexpression of Phosphatidylinositol-3,4,5-Trisphosphate Dependent Rac Exchange Factor 2 (PREX2) is observed in various tumors, including HCC...

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Detalles Bibliográficos
Autores principales: Yang, Ming-Hui, Yen, Chia-Hung, Chen, Yen-Fu, Fang, Cheng-Chieh, Li, Chung-Hsien, Lee, Kuo-Jui, Lin, Yi-Hsiung, Weng, Chien-Hui, Liu, Tze-Tze, Huang, Shiu-Feng, Teh, Bin Tean, Chen, Yi-Ming Arthur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385191/
https://www.ncbi.nlm.nih.gov/pubmed/30796242
http://dx.doi.org/10.1038/s41598-018-36810-5