Angiomotin-p130 inhibits β-catenin stability by competing with Axin for binding to tankyrase in breast cancer

Growing evidence indicates that Angiomotin (Amot)-p130 and Amot-p80 have different physiological functions. We hypothesized that Amot-p130 is a tumor suppressor gene in breast cancer, in contrast with the canonical oncogenicity of Amot-p80 or total Amot. To clarify the role of Amot-p130 in breast ca...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Jiao, Zhang, Xiaoman, Chen, Zheling, Shen, Yanwei, Wang, Fan, Wang, Yaochun, Liu, Yu, Liu, Peijun, Yang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385204/
https://www.ncbi.nlm.nih.gov/pubmed/30792381
http://dx.doi.org/10.1038/s41419-019-1427-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385204/
https://www.ncbi.nlm.nih.gov/pubmed/30792381
http://dx.doi.org/10.1038/s41419-019-1427-2

Ejemplares similares